Notre Dame: 10th Anniversary contains the Notre Dame base game, the New Persons expansion that first appeared in the 2009 alea Treasure Chest, and a new "New Persons" set of nine characters.

In Notre Dame, players take on the roles of the heads of influential families in Paris at the end of the 14th century. In the shadow of the Notre Dame cathedral, the players compete for prosperity and reputation. Each family controls one of the 3–5 boroughs that surround the site of Notre Dame. As head of their family, each player tries — through clever use of their action cards — to advance the power and prestige of their family, but penalties are assessed on those who do not take care of the health of the people who live in their borough. The player with the most prestige at the end wins.